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Case Report

BMB. 2018; 3(3): 37-40


A rare cause of vanishing bile duct syndrome: Hodgkin’s lymphoma

Erdem SUNGER,Elif YORULMAZ,Ahmet Engin ATAY,Burcak KARADENİZ,Husniye Esra PASAOGLU,Sabahattin KAYMAKOGLU,Raim ILIAZ.




Abstract

Vanishing bile duct syndrome (VBDS) is a disorder presented with jaundice and prolonged cholestasis due to intrahepatic cholestasis with paucity of interlobular bile ducts. Liver involvement of Hodgkin's lymphoma (HL) is well-known however VBDS is extremely rare presentation of HL. Lack of well-established pathogenetic mechanism and rarity of disorder may cause diagnostic confusion. We reported a case of VBDS related to Hodgkin’s lymphoma presented with generalized jaundice.

Key words: Cholestasis, Hodgkin's lymphoma, vanishing bile duct syndrome.






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