Original Research |
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The comparison of the efficacy of empirical antibiotic regimens in febrile neutropenic patients
Ramazan Sarı*, İsmet Aydoğdu**, Haluk Şavlı*, Mehmet Bayraktar*** Alper Sevinç* . Abstract | | | |
Objectives: To compare of the efficacy of empirical antibiotic regimens in febrile neutropenic patients in in Adult Hematology Clinic of Turgut Ozal Medical Center.
Material and methods: Four different antibiotic regimens Ceftazidime+Amikacin (n=19), Imipenem+Amikacin (n=14), Cefepime+Amikacin (n=20) and Sulbactam/Cefoperozone+Ami-kacin (n=20) were assessed as initial empirical therapy in febrile neutropenic patients.
Results: Seventy-three febrile neutropenic episodes in 43 patients were evaluated. There was no significant difference in the efficacy and toxicity of antibiotics between the four different regimens (p>0.05).
Conclusion: All of the four empirical antibiotic regimens were equally effective and well tolerated as initial therapy for neutropenic patients with fever.
Key words: Febrile neutropenia, empiric therapy.
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