Home|Journals|Articles by Year|Audio Abstracts
 

Original Research

Ann Med Res. 2002; 9(3): 185-189


Antimicrobial Susceptibility Of Gram-Negative Bacteria Strains Isolated From Urine Samples

Lale Türkmen*

.




Abstract


 

Urinary system infection is a serious health problem that effects millions of people each year. Along with this, the

rapid development of antibiotic resistance observed in the Enterobacteriaceae and Escherichia coli species which are

responsible for the majority of these infections constitutes a serious problem in its treatment. Thus the objective

of this study is to identify the susceptibility of the Gram-negative bacteria isolated from urine samples to 12

different antibiotics (ampicillin, ampicillin/sulbactam, amoxicillin/clavulanic acid, sefalotin, cefoxitin,

cefoperazone, gentamicin, amikacin, tobramycin, trimethoprim/sulfamethoxazole, ciprofloxacin and imipenem).

In identification of the isolated bacteria api 20E (BioMerieux) has been used together with the known

conventional methods. Antibiotic susceptibility is investigated by Kirby-Bauer disc diffusion method.

Totally 91 isolated bacteria were examined. These are identified as follows: 42 as Escherichia coli (462%); 18 as

Klebsiella pneumoniae (19.8%); 13 as Enterobacter cloacae (14.2%); 11 as Proteus vulgaris (12.1%) and 7 as Pseudomonas

aeruginosa (7.7%).

During our studies none of the examinated strains showed resistance to amikacin and imipenem, but high level of

susceptibility to gentamicin and tobramycin (57.0-100%) was observed. Although high resistance to ampicillin,

ampicillin/sulbactam and amoxicillin/clavulanic acid (69.0-100%) was identified in all the strains, the high

increase in the resistance to trimethoprim-sulfamethoxazole (38.9-100%) and ciprofloxacin (11.9-100%) was far

more considerable. Among the cephalosporins resistance to cefalotin was very high (92.8-100%) while the

minimum resistance was identified to cefoperazone (16.7-57.1%).

Key Words: Urinary System Infection, Gram-Negative Bacteria, Antimicrobial Susceptibility.






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.